Short answer · Medically reviewed summary · Last updated: 2026-05-08

Depersonalization Disorder, now more commonly classified under Depersonalization-Derealization Disorder (DPDR), is officially coded as F48.1 in the ICD-10 clinical modification. In the older ICD-9 system, this condition was categorized under code 300.6. What is the clinical classification of Depersonalization Disorder? In current psychiatric practice, Depersonalization Disorder is recognized as a dissociative disorder.

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ICD10 code of Depersonalization Disorder and ICD9 code

ICD-10 and ICD-9 codes for Depersonalization Disorder, with classification details for clinicians, coders and patients.

ICD9 and ICD10 codes of Depersonalization Disorder

Depersonalization Disorder, now more commonly classified under Depersonalization-Derealization Disorder (DPDR), is officially coded as F48.1 in the ICD-10 clinical modification. In the older ICD-9 system, this condition was categorized under code 300.6.



What is the clinical classification of Depersonalization Disorder?


In current psychiatric practice, Depersonalization Disorder is recognized as a dissociative disorder. While the ICD-10 code F48.1 specifically denotes Depersonalization-Derealization Syndrome, clinicians use these codes to facilitate insurance billing and formal medical documentation. Understanding that Depersonalization Disorder is a recognized diagnostic entity is often the first step in validating the experiences of the 239 community members on DiseaseMaps.org who live with this condition.



How is Depersonalization Disorder diagnosed?


Diagnosis of Depersonalization Disorder is primarily clinical, meaning it relies on a detailed psychiatric interview rather than blood tests or imaging. A specialist will look for persistent or recurrent episodes of feeling detached from one's mental processes or body (depersonalization) and/or feeling that the external world is unreal or dreamlike (derealization). Key diagnostic criteria include:



  • Intact reality testing (the patient knows these feelings are not "real").

  • Significant distress or impairment in social, occupational, or other areas of functioning.

  • Symptoms that are not attributable to substance use, medication side effects, or other medical conditions like epilepsy.



Is there a distinction between the ICD-9 and ICD-10 codes?


The transition from ICD-9 (300.6) to ICD-10 (F48.1) reflects a shift toward better capturing the dual nature of Depersonalization Disorder, which frequently involves both depersonalization and derealization. While the codes are administrative, they allow healthcare systems to track the prevalence of Depersonalization Disorder and ensure patients receive appropriate mental health resources.



Next steps



  • Consult a board-certified psychiatrist or clinical psychologist who specializes in dissociative disorders.

  • Connect with the 239 peers on DiseaseMaps.org to share coping strategies and reduce the isolation often associated with Depersonalization Disorder.

  • Keep a symptom journal to track triggers, which can assist your provider in developing a targeted treatment plan, such as Cognitive Behavioral Therapy (CBT).



Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment.



References



  • World Health Organization (WHO), ICD-10 Version: 2019 (F48.1).

  • American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR).

  • NIH Genetic and Rare Diseases Information Center (GARD) - Dissociative Disorders resources.

  • PubMed/NCBI: "Clinical features and management of Depersonalization-Derealization Disorder."

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-05-08
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
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