Short answer · Medically reviewed summary · Last updated: 2026-04-07

Factor V Leiden is a genetic condition and is not contagious, meaning it cannot be spread through contact, blood, or any other form of personal interaction. Understanding the Nature of Factor V Leiden Factor V Leiden is an inherited blood clotting disorder caused by a specific mutation in the F5 gene. Because it is written into your DNA, it is impossible for someone else to "catch" it from you.

5 people with Factor V Leiden have shared their first-person experience on this question at DiseaseMaps.

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Is Factor V Leiden contagious?

Is Factor V Leiden contagious? Clear, medically reviewed answer on transmission, with sources.

Is Factor V Leiden contagious?

Factor V Leiden is a genetic condition and is not contagious, meaning it cannot be spread through contact, blood, or any other form of personal interaction.



Understanding the Nature of Factor V Leiden


Factor V Leiden is an inherited blood clotting disorder caused by a specific mutation in the F5 gene. Because it is written into your DNA, it is impossible for someone else to "catch" it from you. You cannot transmit Factor V Leiden by sharing food, living in the same household, or through physical contact. This condition affects the circulatory system by making blood more prone to clotting, but it is strictly a biological inheritance, not an infectious disease.



Why Misconceptions Exist


Because Factor V Leiden involves blood and often requires medical interventions like anticoagulants or surgery, some individuals may mistakenly associate it with transmissible blood-borne infections. It is important to clarify that while the condition relates to the blood, there is no risk to those around you. You can safely engage in all normal activities, physical intimacy, and social contact without any fear of passing this condition to friends or family members.



Environmental and Genetic Factors


While the condition itself is not triggered by the environment, certain factors can increase the risk of a clot occurring in someone with Factor V Leiden. These include prolonged immobility, pregnancy, the use of oral contraceptives, or surgery. These are not "triggers" that cause the disease—which you are born with—but rather stressors that interact with your existing genetic predisposition. Living with Factor V Leiden requires vigilance regarding these risk factors, but it does not require isolation or special precautions to protect others from you.



Medical Disclaimer: This information is for educational purposes and should not replace professional medical advice, diagnosis, or treatment. Always seek the advice of your hematologist or other qualified health provider with any questions you may have regarding a medical condition.



References



  • NIH Genetic and Rare Diseases Information Center (GARD): Factor V Leiden Thrombophilia

  • Orphanet: Factor V Leiden

  • National Heart, Lung, and Blood Institute (NHLBI): Factor V Leiden

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-04-07
Sources cited: NIH Genetic and Rare Diseases Information Center (GARD): Factor V Leiden Thrombophilia · Orphanet: Factor V Leiden · National Heart, Lung, and Blood Institute (NHLBI): Factor V Leiden
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
6 answers
Factor V is not contagious through bodily fluid contact. It is a genetic mutation and can be hereditary.

Posted Sep 1, 2017 by Stacy 2650
No it is hereditary.

Posted Dec 28, 2017 by shannon 500
No Factor V Leiden is not contagious it is a hereditary gene mutation passed on from your parents there are homozygous and heterozygous meaning you got one gene from one parent or two genes from both parents

Posted Dec 28, 2017 by Timothy Andrew McDonough 850
Factor V Leiden is not contagious it is a genetic blood disorder passed thru DNA by your mother, or father, or both.

Posted Dec 28, 2017 by Barbara 4050
No, it is not contagious.

Posted Dec 28, 2017 by Crystal 700

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I was diagnosed in 2001 after a series of TIA's and a smart neurologist who suspected there was something more to be investigated since I had a history of DVT's and my mother's family has had numerous blood clots.  Since then I was also diagnosed w...
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My name is MARTIN R. LEMIEUX, and for over 20 years now I’ve survived five DVTS – BLOOD CLOTS in my left leg, one clot in my right leg, and another clot in my left pelvic area. As if that wasn’t enough, I’ve also had to manage three massive c...
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In 2010 I was pregnant with my son. Late in my pregnancy I started having horrible swelling in my legs. They were hot, red, and huge. I was placed on maternity leave and put on bed rest. My son was born healthy, but I hemorraged and was given a clot...
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In the spring of 2010, I was working and felt that it was a little difficult to bend my right knee / walk - I felt very little swelling / heat so I thought little of it, especially in light of a prior history of having knee problems in that same leg....

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