I have had lymes since 1999. Didn't have a bullseye rash , didn't know I had lymes for 4 years . Went to Mayo they missed it, went to a clinic in Switzerland they missed it . Did Doxycycline, and other I V treatments for years but what helped the much would at Sierra Integative Medical Center in Reno with DR Fong. It made my lymes better but didn't cure it. That was in 2003 and 2004. I am going back for more treatments soon for a reboost in treatment to feel better .