Short answer · Medically reviewed summary · Last updated: 2026-05-08
Melanoma is typically identified by changes in the size, shape, color, or texture of existing moles or the appearance of a new, unusual-looking spot on the skin. If you notice a lesion that evolves or persists, it is essential to have it evaluated by a dermatologist, as early detection is the most effective way to treat melanoma successfully. What are the early warning signs of melanoma? The most reliable way to identify potential melanoma is by using the "ABCDE" rule, which helps distinguish between benign moles and signs of melanoma.
Melanoma is typically identified by changes in the size, shape, color, or texture of existing moles or the appearance of a new, unusual-looking spot on the skin. If you notice a lesion that evolves or persists, it is essential to have it evaluated by a dermatologist, as early detection is the most effective way to treat melanoma successfully.
The most reliable way to identify potential melanoma is by using the "ABCDE" rule, which helps distinguish between benign moles and signs of melanoma. While many skin spots are normal variations, you should monitor your skin for these specific indicators: Asymmetry (one half does not match the other), Border (irregular, ragged, or blurred edges), Color (uneven shades of brown, black, tan, red, or blue), Diameter (larger than 6mm, or the size of a pencil eraser), and Evolving (a spot that is changing in size, shape, or symptoms like itching or bleeding).
Performing a monthly skin self-exam is vital for early detection. When checking your skin for melanoma, look for the "ugly duckling" sign—a mole that looks distinctly different from all your other spots. You should examine your entire body, including areas not exposed to the sun, such as the soles of your feet, between your toes, and your scalp. If you find a spot that stands out, feels different, or causes concern, document it with a photo to track any changes over time.
If you identify an "ugly duckling" or a spot that follows the ABCDE criteria for melanoma, schedule an appointment with a board-certified dermatologist. Be direct with your physician: "I am concerned about a specific mole that has changed, and I would like a professional skin cancer screening." The gold standard for diagnosis is a physical examination followed by a skin biopsy, where a small tissue sample is sent to a pathologist to check for melanoma cells.
Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment from a qualified healthcare provider.