I have MEN2A, which is often silent ( minimal to no symptoms). For the thyroid cancer, there were no symptoms at all. It was only picked up bec the Drs figured out Mom had MEN2A after her adrenal tumor diagnosis. For the adrenal tumor, I did have "spells", where my heart would race, the blood would drain from my face and I would feel nauseous. It would often happen in the middle of the night, waking me up from sleep. I would also have shaky hands during the spells. The spells would pass if I squatted, but would start back up if I laid down too soon. The spells started before they could pick the adrenal tumors up on MRIs and CT scans.