Short answer · Medically reviewed summary · Last updated: 2023-07-13
Nance-Horan Syndrome is a rare genetic disorder that primarily affects the development of the eyes and teeth. Due to its rarity, the prevalence of this syndrome is relatively low.
What is the prevalence of Nance-Horan Syndrome?
Prevalence of Nance-Horan Syndrome: how many people are affected worldwide, differences by sex and region, with sources.
Nance-Horan Syndrome is a rare genetic disorder that primarily affects the development of the eyes and teeth. Due to its rarity, the prevalence of this syndrome is relatively low. Exact figures regarding its occurrence are not readily available, but it is estimated to affect approximately 1 in 40,000 to 100,000 individuals worldwide.
This syndrome is inherited in an X-linked dominant manner, meaning it predominantly affects males and can be passed on by affected females to their children. The severity of Nance-Horan Syndrome can vary widely among individuals, even within the same family.
Characteristics of this syndrome include various eye abnormalities such as cataracts, microphthalmia (small eyes), strabismus (crossed eyes), and other vision impairments. Dental anomalies like missing or misshapen teeth are also common. Additionally, individuals with Nance-Horan Syndrome may exhibit distinct facial features and intellectual disabilities in some cases.
Diagnosis of Nance-Horan Syndrome is typically based on clinical evaluation, family history, and genetic testing. Although there is no cure for this syndrome, management focuses on addressing specific symptoms and providing appropriate support and care.
