Short answer · Medically reviewed summary · Last updated: 2023-07-13

Non-24-Hour Sleep-Wake Disorder is a rare circadian rhythm sleep disorder that affects the synchronization of an individual's sleep-wake cycle with the 24-hour day-night cycle. It primarily occurs in individuals who are totally blind, as their lack of light perception disrupts the body's natural ability to regulate sleep and wakefulness. Estimating the exact prevalence of Non-24-Hour Sleep-Wake Disorder is challenging due to its rarity and underdiagnosis.

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What is the prevalence of Non-24-Hour Sleep-Wake Disorder?

Prevalence of Non-24-Hour Sleep-Wake Disorder: how many people are affected worldwide, differences by sex and region, with sources.

Prevalence of Non-24-Hour Sleep-Wake Disorder

Non-24-Hour Sleep-Wake Disorder is a rare circadian rhythm sleep disorder that affects the synchronization of an individual's sleep-wake cycle with the 24-hour day-night cycle. It primarily occurs in individuals who are totally blind, as their lack of light perception disrupts the body's natural ability to regulate sleep and wakefulness.


Estimating the exact prevalence of Non-24-Hour Sleep-Wake Disorder is challenging due to its rarity and underdiagnosis. However, studies suggest that it affects a significant proportion of blind individuals. Research conducted on blind individuals in the United States estimated that approximately 50-70% of totally blind individuals experience Non-24-Hour Sleep-Wake Disorder at some point in their lives.


It is important to note that Non-24-Hour Sleep-Wake Disorder can have a significant impact on an individual's daily functioning and overall quality of life. The disrupted sleep patterns can lead to excessive daytime sleepiness, difficulty concentrating, and impaired cognitive function.


While there is no cure for Non-24-Hour Sleep-Wake Disorder, various strategies such as light therapy, melatonin supplementation, and maintaining a consistent sleep schedule can help manage the symptoms and improve sleep-wake synchronization.


Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2023-07-13
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
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My sleep disorder is congenital. It took me a lifetime to figure out and understand what it is and why I have it. I'm currently 43 years old. I was originally diagnosed with DSPS (delayed sleep phase syndrome) when I was 16 years old. However, ...

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