For some the cause is unclear. It seems to affect females with a certain body type more per my doctor. Also heavy steroid use has been shown to cause osteonecrosis especially in females. I believe that is how I acquired the disease as I was in the military and treated with heavy steroids due to wounds I sustained while in the service.
Avascular necrosis occurs when blood flow to a bone is interrupted or reduced. Reduced blood supply can be caused by:
Joint or bone trauma. An injury, such as a dislocated joint, might damage nearby blood vessels. Cancer treatments involving radiation also can weaken bone and harm blood vessels.
Fatty deposits in blood vessels. The fat (lipids) can block small blood vessels, reducing the blood flow that feeds bones.
Certain diseases. Medical conditions, such as sickle cell anemia and Gaucher's disease, also can cause diminished blood flow to bone.
Unknown. Some reported causes center around a lack of suffient blood supply to the area, and however, I there are many reasons for that. In my own case the culpret was a broken femur that didn't heal. I am sure there are many other and different causes, such especially among those that have bilateral ON.
The “known” cause are:
Steroid use
Extreme alcohol intake
Sickle cell disease
Circulatory problems
Illegal drug use
Trauma to the area
Or Idiopathic (no known cause)
All of the causes are still being investigated. What they suspect so far are steroid use, heavy alcohol use, and smoking. Now this is an area where genetic research will be helpful.
Osteonecrosis may be caused by physical injury to the joint (ie car crash). Alcoholism can cause osteonecrosis. Corticosteroid treatment (for example prednisone, prednisone) is also linked to the condition, particularly long courses of high dose corticosteroids. The mechanism that alcohol or steroids can cause osteonecrosis is unknown. In 40% of cases the cause is unknown, also called 'idiopathic'
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My on line profile is listed as Jenny from the Block. I am 53, today in September 2018.
Until now, I have had a pretty wonderful and really tough life. My Holy Spirit has always been with me and brought me through many da...
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