Short answer · Medically reviewed summary · Last updated: 2026-05-08

Osteonecrosis, also known as avascular necrosis, is primarily diagnosed through specialized imaging when bone tissue dies due to a temporary or permanent loss of blood supply. You may suspect Osteonecrosis if you experience persistent, deep-seated joint pain that worsens with weight-bearing and does not improve with standard rest or physical therapy. What are the early signs of Osteonecrosis? In the early stages, Osteonecrosis often presents with mild joint pain that may come and go.

11 people with Osteonecrosis have shared their first-person experience on this question at DiseaseMaps.

14

How do I know if I have Osteonecrosis?

Could you have Osteonecrosis? Early signs that prompted real patients to seek diagnosis, plus medically reviewed guidance.

Do I have Osteonecrosis?

Osteonecrosis, also known as avascular necrosis, is primarily diagnosed through specialized imaging when bone tissue dies due to a temporary or permanent loss of blood supply. You may suspect Osteonecrosis if you experience persistent, deep-seated joint pain that worsens with weight-bearing and does not improve with standard rest or physical therapy.



What are the early signs of Osteonecrosis?


In the early stages, Osteonecrosis often presents with mild joint pain that may come and go. As the condition progresses, the pain typically becomes constant. Common early warning signs include:



  • Pain in the hip, knee, shoulder, or ankle that intensifies during activity.

  • A dull ache or throbbing sensation in the groin or thigh area.

  • Limited range of motion in the affected joint.

  • Limping if the Osteonecrosis is located in the hip or lower extremity.



How is Osteonecrosis diagnosed by a physician?


Since early-stage Osteonecrosis is often invisible on standard X-rays, diagnosis requires more sensitive imaging. If you suspect you have this condition, ask your doctor for an MRI, which is considered the gold standard for early detection. A clinical evaluation will focus on your medical history, specifically looking for risk factors like long-term corticosteroid use, alcohol intake, or history of joint trauma.



When should I seek urgent medical evaluation?


If you experience sudden, severe joint pain that renders you unable to bear weight or perform daily movements, seek immediate medical attention. These "red flags" can indicate a structural collapse of the bone, a common complication of advanced Osteonecrosis. Do not wait for symptoms to resolve if the pain is acute and prevents normal function.



How can I advocate for my health?


If your concerns about Osteonecrosis are dismissed, request a referral to an orthopedic surgeon who specializes in joint preservation. Bring a detailed log of your pain patterns and any known risk factors to your appointment. You are your own best advocate; if you feel your symptoms persist, do not hesitate to seek a second opinion from a specialist familiar with bone metabolism and degenerative joint diseases.



Next steps



  • Consult an orthopedic specialist or a rheumatologist to discuss your joint pain.

  • Request an MRI of the affected joint to rule out or confirm Osteonecrosis.

  • Join the 410 members at DiseaseMaps.org who are navigating life with Osteonecrosis to share experiences and coping strategies.



Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment.



References



  • NIH Genetic and Rare Diseases Information Center (GARD): Osteonecrosis

  • Orphanet: Avascular necrosis of bone

  • American Academy of Orthopaedic Surgeons (AAOS): Osteonecrosis of the Hip

  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-05-08
Sources cited: NIH Genetic and Rare Diseases Information Center (GARD): Osteonecrosis · Orphanet: Avascular necrosis of bone · American Academy of Orthopaedic Surgeons (AAOS): Osteonecrosis of the Hip · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · WHO
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
12 answers
Many don't know until it is too late. Listen to your body, if you think there is something wrong get it looked at.

Posted Jun 16, 2017 by Austin 4830
See your doctor. Usually DX with Xray

Posted Jun 30, 2017 by Dave 2270
Only an Xray or MRI will tell for sure. The type of pain will be unlike anything you most likely have experienced. It is a persistent deep core bone pain that feels like it radiates from within the bone outward. Pain may persist whether weight bearing or at rest. Often in the middle of the night you may ache or multiple joints will ache.

Posted Sep 27, 2017 by Alan 900
The pain is usually what tells you something is wrong, I which leads to the testing mentioned above.

Posted Nov 3, 2017 by Pamela 1600
An MRI of the affected joint.

Posted Jun 11, 2018 by Rob 1500
Server pain in a joint, unable to move it, burning, swelling, unable to sleep, go to a GP first and a special doctor who has experience in it

Posted Jun 11, 2018 by Megan 2500
Severe deep ache in your joints that progressively gets worse. Medical tests including an MRI will confirm the diagnosis

Posted Nov 13, 2018 by Scott 3050
If you have pain that doesn’t go away or gets worse, get an mri or x-ray.

Posted Aug 27, 2019 by Cheryl 2800
MRI diagnosis tool
If you have pain

Posted Feb 28, 2020 by Lisa j 1700
Ain is the main symptom of osteonecrosis. If you have pain in a joint whenever you put weight on it, or if you have constant pain that's getting worse, not better you should seek medical advice. Your primary care provider or local doctor can assist you. There are more common causes for pain like this and the doctor will want to check for them. You can ask for an x-ray of the joint. Ask for an xray even if they want you to get an ultrasound too. Osteonecrosis cannot be seen on an ultrasound, your Dr will need an xray to identify osteonecrosis.

Posted Mar 15, 2020 by Caitlin 3050
Translated from spanish Improve translation
Experienced sudden intense pain in the bone or joint

Posted May 18, 2017 by Javier 2150

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