Is Paroxysmal Kinesigenic Choreathetosis / Dyskinesia contagious?

Paroxysmal Kinesigenic Choreathetosis (PKC), also known as Paroxysmal Kinesigenic Dyskinesia (PKD), is not a contagious condition and cannot be transmitted to others through touch, proximity, or social interaction. It is a neurological disorder primarily driven by genetic mutations, meaning there is zero risk of "catching" this disease from a friend, family member, or colleague.

What causes Paroxysmal Kinesigenic Choreathetosis?

Paroxysmal Kinesigenic Choreathetosis is primarily a genetic movement disorder. In a significant number of cases, it is caused by mutations in the PRRT2 gene, which plays a crucial role in neurotransmitter release. Because it is rooted in your DNA, it is biologically impossible for it to spread like a virus or infection. The condition manifests as brief, recurrent episodes of involuntary movements triggered by sudden voluntary motion.

Why is there confusion regarding contagion?

Because Paroxysmal Kinesigenic Dyskinesia involves sudden, involuntary physical movements, bystanders unfamiliar with the condition may mistakenly fear it is an infectious outbreak or a behavioral contagion. This stigma is entirely unfounded. Paroxysmal Kinesigenic Choreathetosis is a physiological reaction to specific neurological stimuli, and the 7 members of our DiseaseMaps community living with this condition face no risk to their peers or loved ones.

Are there environmental triggers for Paroxysmal Kinesigenic Dyskinesia?

While the condition is not contagious, it is highly sensitive to specific environmental and physical triggers. These include:

• Sudden voluntary movement: Standing up quickly or starting to run.


• Startle response: Sudden noises or unexpected physical contact.


• Emotional stress: Heightened anxiety or excitement can sometimes lower the threshold for an attack.


• Fatigue: Lack of sleep or physical exhaustion may increase the frequency of episodes.

Next steps

• Consult a neurologist specializing in movement disorders to discuss genetic testing for the PRRT2 gene.


• Join our community at DiseaseMaps.org to connect with others who understand the reality of living with Paroxysmal Kinesigenic Choreathetosis.


• Educate family and friends about the non-contagious nature of Paroxysmal Kinesigenic Dyskinesia to reduce unnecessary social anxiety.

Medical disclaimer: This content is for educational purposes only and does not constitute medical advice, diagnosis, or treatment; always seek the advice of your physician with any questions regarding a medical condition.

References

• NIH Genetic and Rare Diseases Information Center (GARD): Paroxysmal Kinesigenic Dyskinesia.


• Orphanet: Paroxysmal kinesigenic choreoathetosis (ORPHA:1669).


• OMIM (Online Mendelian Inheritance in Man): Dyskinesia, familial kinesigenic, 1; FKS1 (#128200).