Relapsing Polychondritis (RP) is a rare, progressive condition characterised by recurrent episodes of inflammation of cartilaginous structures. These include the ears, nose, upper respiratory tract, chest wall and joints. Other organs and tissues may also become involved such as the eye, inner ear, heart, blood vessels and kidneys.
The exact cause of Relapsing Polychondritis (RP) is not known. However, it is believed to be an autoimmune disorder where the body's immune system starts attacking its own healthy cells believing them to be foreign.
RP has an episodic pattern with periods of intense inflammation and periods of remission and dependant on the severity of the inflammatory process, often requiring the use of immune suppressant medications.
RP can be life threatening, debilitating and difficult to diagnose and prognosis is variable, depending on organ involvement and treatment complications. Where the disease is mild or responds quickly to treatment, there is a good prognosis.
Relapsing Polychondritis is also known by other names such as Meyenburg Altherr Uehlinger syndrome, chronic atrophic polychondritis and Von Meyenburg syndrome.