Short answer · Medically reviewed summary · Last updated: 2023-07-13
Smallpox, caused by the variola virus, is a highly contagious and often fatal disease that plagued humanity for centuries. The severity of smallpox varied, with different strains having different mortality rates.
Smallpox, caused by the variola virus, is a highly contagious and often fatal disease that plagued humanity for centuries. The severity of smallpox varied, with different strains having different mortality rates. Historically, the average fatality rate for smallpox ranged from 30% to 40%, meaning that about 3 to 4 out of every 10 infected individuals would not survive the illness.
The course of smallpox typically involved several stages. Initially, individuals would experience flu-like symptoms such as fever, headache, and fatigue. After a few days, characteristic skin lesions would appear, progressing from macules to papules, vesicles, pustules, and finally scabs. The severity of the disease and the individual's overall health played a significant role in determining the outcome.
Survival rates for smallpox were influenced by various factors:
Despite the severity of smallpox, the majority of infected individuals did survive. However, the disease often left survivors with significant physical and emotional scars, including disfiguring skin marks and potential vision loss.
It is important to note that smallpox was eradicated globally in 1980 through an intensive vaccination campaign led by the World Health Organization. Today, the only known remaining samples of the virus are securely stored in laboratories, significantly reducing the risk of natural infection.