There are underlying conditions that are hereditary and carry a risk of getting the cysts.
In addition, there is medical evidence that collagen mutations or Connective Tissue Disorders such as Marfans Syndrome, Ehlers Danlos Syndrome, Sjögren's, Loeys-Dietz, Lupus, MTCD (Mixed Connective Tissue Disorders), UCTD (Undierentiated Connective Tissue Disorders) can update to the development of cysts. There are many
patients with Tarlov cysts who also have any of the above conditions or a family member who has a
of the above conditions with or without Tarlov Cysts. As far as is known from the medical history, is that there is therefore a genetic basis for the development of the cysts and that the disease is chronic. In some families there are several people with the overpressure syndrome and/or/ Tarlov cysts, but it is mainly women who are affected. However, men can also get this disease. What has been reported so far in the medical studies is that the cysts are often at a somewhat start to become symptomatic later in life, but it is now known that this can also be done at a very young age occur, even in infants/babies.