Short answer · Medically reviewed summary · Last updated: 2026-04-07
Uterine fibroids, also known as leiomyomas, are highly common benign tumors of the uterus, estimated to affect up to 70% to 80% of women by the age of 50. Prevalence and Classification While often grouped within rare disease discussions due to the severe health impact on specific individuals, Uterine Fibroids are clinically classified as a common condition rather than a rare disease. Because they occur exclusively in the uterus, they affect only biological females.
What is the prevalence of Uterine Fibroids?
Prevalence of Uterine Fibroids: how many people are affected worldwide, differences by sex and region, with sources.
Uterine fibroids, also known as leiomyomas, are highly common benign tumors of the uterus, estimated to affect up to 70% to 80% of women by the age of 50.
Prevalence and Classification
While often grouped within rare disease discussions due to the severe health impact on specific individuals, Uterine Fibroids are clinically classified as a common condition rather than a rare disease. Because they occur exclusively in the uterus, they affect only biological females. The incidence is difficult to pinpoint precisely because many individuals remain asymptomatic and never seek medical evaluation, leading to significant underdiagnosis.
Demographic and Geographic Variations
Research indicates that Uterine Fibroids exhibit significant ethnic and racial disparities. Studies, including data from the NIH, consistently show that Black women are more likely to develop fibroids at an earlier age, experience larger and more numerous tumors, and report more severe symptoms compared to white women. While the condition can develop at any age during reproductive years, the peak incidence of Uterine Fibroids typically occurs in women in their 30s and 40s, with a gradual decline after menopause.
Challenges in Data Collection
The primary challenge in establishing exact prevalence statistics for Uterine Fibroids is the high rate of asymptomatic cases. Many women may have small fibroids that are never detected via imaging or clinical examination. Consequently, clinical literature often relies on symptomatic cohorts, which may skew the perceived severity of the condition. At DiseaseMaps.org, the 104 members currently sharing their experiences provide a vital, real-world perspective that complements these broad epidemiological figures by highlighting the lived reality of those seeking support for their symptoms.
Disclaimer: This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
References
- NIH Genetic and Rare Diseases Information Center (GARD) - Uterine Fibroids
- Office on Women’s Health (OWH), U.S. Department of Health and Human Services
- PubMed/National Library of Medicine - Epidemiology and Risk Factors for Uterine Fibroids
