Personlly, the most limiting for me are the abdominal attacks. They come on randomly, and I never know how long they will last. Getting rid of the abdominal attacks would definitely be my first hii with. My facial swelling occurs less frequently, however, those are the the scariest/most life threatening of the attacks. To be completely honest, the most difficult part about living with HAE isn’t the attacks themselves. (Don’t get me wrong, those are bad), but if I could truly change one thing, it would be the unpredictability in which the attacks occur. It is impossible to live a normal life when you never know if you’ll end up being sock last minute, and it’s truly a terrible way for someone to live their life.