It is a clinical diagnosis which means there is NOT a test. There are international standards with a point system. Everyone must have oral apthous ulcers. It is the hallmark of the disease we all share. If you break out three times or more a year, you get the first point. It's best to be evaluated by a Dermatologist who specializes in rheumatology and have a punch biopsy done. Don't worry, it isn't too painful and heals quickly. Then, you need to have two or more of the following in order to be diagnosed:
1) Recurrent genital ulcerations - we are usually misdiagnosed with HSV despite a negative test
2) Eye lesions (uveitis or retinal vasculitis) observed by an opthalmologist which is the leading cause of blindness in Japan, so don't mess around. You should keep eye drops on hand.
3) Skin lesions (erythema nodosum, pseudofolliculitis, papulopustular lesions, acneiform nodules) found in adult patients not being treated with corticosteroids that usually present on the arms or legs. They can be extremely painful. They usually look like a dry version of the ulcers in our mouths.
4) Positive "pathergy test" read by a physician within 24-48 hours of testing which is why we have false positives for TB tests.
I have had all five, but currently have three. I have been in remission and only had one.