Short answer · Medically reviewed summary · Last updated: 2026-05-08
Cyclic Neutropenia is a rare hematological disorder characterized by recurrent episodes of abnormally low levels of neutrophils, typically occurring in a 21-day cycle. It is primarily known by this name, though it is occasionally referred to in older literature as Periodic Neutropenia or Cyclic Hematopoiesis. What are the primary synonyms for Cyclic Neutropenia? While Cyclic Neutropenia is the standard medical term used globally, you may encounter several alternative names in medical records or historical texts.
Cyclic Neutropenia synonyms
Other names for Cyclic Neutropenia: synonyms, acronyms and related terms used by doctors and patients.
Cyclic Neutropenia is a rare hematological disorder characterized by recurrent episodes of abnormally low levels of neutrophils, typically occurring in a 21-day cycle. It is primarily known by this name, though it is occasionally referred to in older literature as Periodic Neutropenia or Cyclic Hematopoiesis.
What are the primary synonyms for Cyclic Neutropenia?
While Cyclic Neutropenia is the standard medical term used globally, you may encounter several alternative names in medical records or historical texts. Understanding these synonyms is essential for patients navigating diverse databases. Common synonyms and related terms include:
- Periodic Neutropenia: Frequently used to describe the rhythmic nature of the condition.
- Cyclic Hematopoiesis: An older term reflecting that other blood cell lines may also fluctuate, though neutrophils are most severely affected.
- Leukopenia-Periodic: A rare, descriptive term found in older clinical archives.
How is the condition classified in medical systems?
Medical professionals prefer the term Cyclic Neutropenia because it precisely describes the clinical hallmark of the disease. In major classification systems, you will find it listed as follows:
- OMIM (Online Mendelian Inheritance in Man): Listed under ID #162800.
- Orphanet: Classified under the ORPHA code 643.
- ICD-10/11: Coded under D70.4 (Cyclic neutropenia).
Why does Cyclic Neutropenia have multiple names?
The nomenclature for Cyclic Neutropenia has evolved alongside our understanding of its genetic basis. Historically, researchers labeled it based on observed symptoms (periodic drops in blood counts). However, once the mutation in the ELANE gene was identified, the focus shifted to the neutropenic aspect. Today, Cyclic Neutropenia remains the preferred clinical term because it clearly communicates the diagnostic cycle to hematologists and immunologists.
Is there a community for those with this diagnosis?
Navigating a rare diagnosis like Cyclic Neutropenia can be isolating. Currently, 25 people with Cyclic Neutropenia have joined the DiseaseMaps.org community to share their experiences, symptom tracking, and management strategies, providing a vital resource for those seeking peer support.
Next steps
- Consult a hematologist or immunologist to confirm your specific diagnosis through ELANE gene testing.
- Join the 25 members in the DiseaseMaps Cyclic Neutropenia community to share your journey.
- Keep a detailed log of your symptom cycles to assist your physician in planning potential G-CSF therapy.
Medical disclaimer: This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment; always seek the guidance of a qualified healthcare provider.
References
- NIH Genetic and Rare Diseases Information Center (GARD): Cyclic Neutropenia overview.
- Orphanet: Rare disease database entry for Cyclic Neutropenia.
- OMIM: Entry 162800 regarding the genetic basis of Cyclic Neutropenia.
- PubMed/NCBI: Clinical literature on ELANE-related neutropenia.
