Short answer · Medically reviewed summary · Last updated: 2026-05-08
Factor V Deficiency, also known as Owren's disease or parahemophilia, is a rare autosomal recessive bleeding disorder caused by the insufficient production or function of the coagulation protein Factor V. Because this condition has been described under several names throughout medical history, it is important for patients to recognize that these terms all refer to the same deficiency of the clotting protein necessary for normal blood coagulation. What are the common synonyms for Factor V Deficiency? Medical literature and historical records often refer to Factor V Deficiency by several alternative names.
Factor V Deficiency synonyms
Other names for Factor V Deficiency: synonyms, acronyms and related terms used by doctors and patients.
Factor V Deficiency, also known as Owren's disease or parahemophilia, is a rare autosomal recessive bleeding disorder caused by the insufficient production or function of the coagulation protein Factor V. Because this condition has been described under several names throughout medical history, it is important for patients to recognize that these terms all refer to the same deficiency of the clotting protein necessary for normal blood coagulation.
What are the common synonyms for Factor V Deficiency?
Medical literature and historical records often refer to Factor V Deficiency by several alternative names. The term "parahemophilia" was coined by Dr. Paul Owren in 1947, who first identified the condition, leading many older texts to refer to it as "Owren's disease." Other recognized synonyms include "labile factor deficiency" and "proaccelerin deficiency," reflecting the historical understanding of the protein's unstable nature in stored blood plasma.
Why does this condition have so many names?
The variety of names for Factor V Deficiency stems from the rapid evolution of hematology in the mid-20th century. As researchers identified the specific coagulation factors involved in the blood-clotting cascade, they often assigned names based on the factor’s function (e.g., "proaccelerin") or the physician who discovered the clinical presentation. Today, the medical community prefers the standardized nomenclature of Factor V Deficiency to avoid confusion with other clotting factor disorders.
How is the condition classified officially?
To ensure clarity in international medical records, Factor V Deficiency is categorized within major medical databases using specific codes:
- OMIM (Online Mendelian Inheritance in Man): #227400
- Orphanet: ORPHA324 (categorized as a rare coagulation defect)
- ICD-10-CM: D68.2 (Hereditary deficiency of other clotting factors)
Next steps
- Consult with a hematologist to confirm your diagnosis through specific coagulation factor assays.
- Connect with others living with this condition on DiseaseMaps.org to share experiences.
- Request a genetic consultation to understand the inheritance pattern if you are planning to start a family.
- Always keep a medical alert card in your wallet identifying your Factor V Deficiency to ensure proper care during emergencies.
Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment.
