Short answer · Medically reviewed summary · Last updated: 2026-05-08
Multiple Systems Atrophy (MSA) is classified under ICD-10 code G90.3, which refers to idiopathic peripheral autonomic neuropathy or multi-system degeneration. In the older ICD-9-CM classification system, Multiple Systems Atrophy was typically coded under 333.0, representing disorders of the basal ganglia. What is the clinical nature of Multiple Systems Atrophy? Multiple Systems Atrophy is a rare, progressive neurodegenerative disorder characterized by a combination of symptoms affecting the autonomic nervous system and motor control.
2 people with Multiple Systems Atrophy have shared their first-person experience on this question at DiseaseMaps.
ICD10 code of Multiple Systems Atrophy and ICD9 code
ICD-10 and ICD-9 codes for Multiple Systems Atrophy, with classification details for clinicians, coders and patients.
Multiple Systems Atrophy (MSA) is classified under ICD-10 code G90.3, which refers to idiopathic peripheral autonomic neuropathy or multi-system degeneration. In the older ICD-9-CM classification system, Multiple Systems Atrophy was typically coded under 333.0, representing disorders of the basal ganglia.
What is the clinical nature of Multiple Systems Atrophy?
Multiple Systems Atrophy is a rare, progressive neurodegenerative disorder characterized by a combination of symptoms affecting the autonomic nervous system and motor control. Because Multiple Systems Atrophy involves the widespread loss of nerve cells in specific areas of the brain, it often presents with complex, overlapping symptoms that require multidisciplinary care.
How is Multiple Systems Atrophy classified?
Clinicians generally categorize Multiple Systems Atrophy into two main clinical subtypes based on the predominant symptoms at the time of diagnosis:
- MSA-P (Parkinsonian type): Characterized by slowness of movement (bradykinesia), rigidity, and tremors, often mimicking Parkinson’s disease.
- MSA-C (Cerebellar type): Characterized primarily by ataxia, which includes balance issues, gait instability, and uncoordinated movements.
What are the primary clinical challenges of Multiple Systems Atrophy?
Managing Multiple Systems Atrophy is difficult because there is currently no cure, and treatments focus exclusively on symptom management. Patients in the DiseaseMaps community, which includes 911 members living with Multiple Systems Atrophy, frequently report that addressing orthostatic hypotension, urinary retention, and central sleep apnea is essential for maintaining quality of life. Because this condition impacts multiple systems, including the circulatory, digestive, and respiratory systems, it requires a highly personalized approach to care.
Next steps
- Consult with a movement disorder specialist or a neurologist experienced in autonomic failure to manage complex symptoms.
- Join the DiseaseMaps community to connect with 911 other individuals sharing experiences with Multiple Systems Atrophy.
- Speak with your primary care physician about optimizing your care plan to include physical, occupational, and speech therapy.
Medical disclaimer: This information is for educational purposes only and does not constitute professional medical advice, diagnosis, or treatment; always seek the advice of your physician regarding a medical condition.
References
- NIH Genetic and Rare Diseases Information Center (GARD) - Multiple System Atrophy
- Orphanet: Rare Disease Database (ORPHA:597)
- Online Mendelian Inheritance in Man (OMIM) - MSA entry #146500
- Multiple System Atrophy Coalition (MSA Coalition)
http://www.icd10data.com/ICD10CM/Codes/G00-G99/G89-G99/G90-/G90.3
2015 ICD9-CM code for Multiple System Atrophy: 333.0
http://www.icd9data.com/2015/Volume1/320-389/330-337/333/333.0.htm
US Social Security Compassionate Care Allowance description of Multiple System Atrophy: https://secure.ssa.gov/poms.nsf/lnx/0423022630
Posted Jul 11, 2017 by Pam Bower 2952
Multi-system degeneration of the autonomic nervous system
2016 2017 2018 Billable/Specific Code
G90.3 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
The 2018 edition of ICD-10-CM G90.3 became effective on October 1, 2017.
This is the American ICD-10-CM version of G90.3 - other international versions of ICD-10 G90.3 may differ.
Applicable To
Neurogenic orthostatic hypotension [Shy-Drager]
Type 1 Excludes
orthostatic hypotension NOS (I95.1)
The following code(s) above G90.3 contain annotation back-references that may be applicable to G90.3:
G00-G99 Diseases of the nervous system
G90 Disorders of autonomic nervous system
Approximate Synonyms
Multi-system degeneration of autonomic nervous system
Multiple system atrophy, parkinson's variant
Multisystem degeneration of autonomic nervous system
Parkinsonism with orthostatic hypotension
Parkinsons variant
Shy drager syndrome
ICD-10-CM G90.3 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0):
056 Degenerative nervous system disorders with mcc
057 Degenerative nervous system disorders without mcc
Convert G90.3 to ICD-9-CM
Code History
2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
Code annotations containing back-references to G90.3:
Type 1 Excludes: I95.1, G21, R03.1, R55
Type 2 Excludes: G23
Diagnosis Index entries containing back-references to G90.3:
Degeneration, degenerative
multi-system G90.3
Hypotension (arterial) (constitutional) I95.9
orthostatic (chronic) I95.1
neurogenic G90.3
neurogenic, orthostatic G90.3
Parkinsonism (idiopathic) (primary) G20
with neurogenic orthostatic hypotension G90.3 (symptomatic)
Shy-Drager syndrome G90.3
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
Posted Mar 23, 2018 by [email protected] 3020
