Short answer · Medically reviewed summary · Last updated: 2026-05-08

Multiple Systems Atrophy is not contagious; it is a progressive neurodegenerative disorder and cannot be spread through contact, bodily fluids, or any form of social interaction. You are at zero risk of developing Multiple Systems Atrophy by living with, caring for, or spending time with someone diagnosed with the condition. What causes Multiple Systems Atrophy? Multiple Systems Atrophy is caused by the abnormal accumulation of a protein called alpha-synuclein within the brain's supporting cells, known as oligodendrocytes.

3 people with Multiple Systems Atrophy have shared their first-person experience on this question at DiseaseMaps.

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Is Multiple Systems Atrophy contagious?

Is Multiple Systems Atrophy contagious? Clear, medically reviewed answer on transmission, with sources.

Is Multiple Systems Atrophy contagious?

Multiple Systems Atrophy is not contagious; it is a progressive neurodegenerative disorder and cannot be spread through contact, bodily fluids, or any form of social interaction. You are at zero risk of developing Multiple Systems Atrophy by living with, caring for, or spending time with someone diagnosed with the condition.



What causes Multiple Systems Atrophy?


Multiple Systems Atrophy is caused by the abnormal accumulation of a protein called alpha-synuclein within the brain's supporting cells, known as oligodendrocytes. This accumulation leads to the death of nerve cells in specific areas of the brain that control autonomic functions, balance, and movement. It is not caused by viruses, bacteria, or any infectious agent. Currently, medical research indicates that Multiple Systems Atrophy is a sporadic condition, meaning it occurs randomly without a clear hereditary pattern or environmental "trigger" that a person can catch or transmit to others.



Why is there confusion regarding contagion?


Because Multiple Systems Atrophy is a rare and complex condition, the lack of public awareness can lead to unfounded fears. Some people may mistakenly associate it with infectious neurological conditions or assume that because it affects multiple body systems, it must be systemic like an infection. However, clinical evidence is definitive: there is no transmission pathway. Living with someone with Multiple Systems Atrophy involves zero risk of infection.



What are the primary characteristics of the condition?


Multiple Systems Atrophy impacts various bodily systems, leading to a cluster of symptoms that often progress over time. Key features include:



  • Autonomic failure: Severe orthostatic hypotension (drop in blood pressure upon standing) and urinary retention.

  • Motor symptoms: Slowed movements (bradykinesia), balance issues, and one-sided weakness.

  • Respiratory and sleep issues: Central sleep apnea and stridor (high-pitched breathing).

  • Sexual dysfunction: Frequently presenting as erectile dysfunction in early stages.



Next steps



  • Consult with a neurologist specializing in movement disorders to manage symptom progression.

  • Join the 911 members of the DiseaseMaps.org community to share experiences and find emotional support.

  • Educate family and friends about the non-contagious nature of Multiple Systems Atrophy to reduce social isolation.



Medical disclaimer: This content is for informational purposes only and does not constitute professional medical advice, diagnosis, or treatment.



References



  • NIH Genetic and Rare Diseases Information Center (GARD) - Multiple System Atrophy

  • Orphanet: Rare Disease Database (ORPHA:587)

  • Multiple System Atrophy Coalition (MSAC)

  • National Institute of Neurological Disorders and Stroke (NINDS)

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-05-08
Sources cited: NIH Genetic and Rare Diseases Information Center (GARD) - Multiple System Atrophy · Orphanet: Rare Disease Database (ORPHA:587) · Multiple System Atrophy Coalition (MSAC) · National Institute of Neurological Disorders and Stroke (NINDS)
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
4 answers
As of 2018 there has never been a case reported of multiple system atrophy spreading from person to person.

Posted Jul 11, 2017 by Pam Bower 2952
No..................

Posted Jan 4, 2018 by Jan 1500
No. It is a neurological disease. Even if it were determined to be a prion disease (as some studies have suggested) you would have to eat someone’s brain to get it.

So just to be safe, don’t eat human brains.

Posted Mar 23, 2018 by [email protected] 3020

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Chicago and area MSA support group meeting April 17th 2-4PM Goodwill Crystal Lake - 1016 Central Park Drive, Crystal Lake, IL. Contact John Standley [email protected] 815-403-2221

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