Short answer · Medically reviewed summary · Last updated: 2023-07-13
SAPHO syndrome is a rare chronic disorder that affects the bones, joints, and skin. The acronym stands for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis, which are the main symptoms associated with this condition.
What is SAPHO syndrome
What is SAPHO syndrome? Plain-language, medically reviewed definition plus the lived reality told by patients.
SAPHO syndrome is a rare chronic disorder that affects the bones, joints, and skin. The acronym stands for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis, which are the main symptoms associated with this condition.
Synovitis refers to the inflammation of the synovial membrane, which lines the joints. This can lead to joint pain, swelling, and stiffness.
Acne and pustulosis are skin manifestations commonly seen in individuals with SAPHO syndrome. These skin conditions can cause painful acne-like lesions and pustules on the skin.
Hyperostosis refers to abnormal bone growth, particularly in the spine, chest, and long bones. This can result in bone pain and deformities.
Osteitis is the inflammation of bone tissue, which can further contribute to bone pain and tenderness.
The exact cause of SAPHO syndrome is unknown, but it is believed to involve a combination of genetic and environmental factors. Diagnosis is often challenging due to the rarity of the condition and the similarity of symptoms to other diseases. Treatment typically focuses on managing symptoms through a combination of medications, physical therapy, and lifestyle modifications.
