Methotrexate is used as therapy for arthritis, retinal vasculitis and chronic central nervous system lesions
Tetracycline is used in the treatment of oral ulcers
Colchicine is used in the treatment of arthritis, oral ulcers, genital ulcers, erythema nodosum,
Thalidomide is used to treat oral and genital ulcers
Dapsone is used as alternative therapy for oral and genital ulcers and for pseudofolliculitis
Pentoxifylline is used orally as therapy for oral ulcers, genital ulcers, pseudofolliculitis and erythema nodosum
Sulfasalazine is used as therapy for arthritis
Aspirin is used as therapy for arteritis, venous thrombosis and chronic progressive central nervous system lesions
MAGIC mouthwash is used to alleviate pain in the oral mucosa