10
Which are the causes of Hereditary multiple exostoses?
Causes of Hereditary multiple exostoses explained: genetic and environmental factors, reviewed against medical sources, plus patient perspectives.
Hereditary multiple exostosis is inherited as an autosomal dominant genetic condition. Dominant genetic disorders occur when only a single copy of an abnormal gene is necessary to cause a particular disease. The abnormal gene can be inherited from either parent or can be the result of a new mutation in the affected individual. For some affected individuals no mutation in either gene is detected. In almost all these cases, the “mutation negative” patients do not have a familial history for exostoses. The risk of passing the abnormal gene from affected parent to offspring is 50% for each pregnancy. The risk is the same for males and females.
Posted Nov 30, 2017 by Zahra 1950
